Sleep, Circadian Rhythm & Fatigue

This report may be useful if you experience any of these symptoms:

Your body runs on an internal 24-hour clock, coordinated by a master clock behind your eyes. It decides when you feel sleepy, when you feel alert, and when hormones rise and fall. Good sleep needs two things working together: enough sleep pressure, and good timing. The genes in this report control that system- the core clock gears, the melatonin signal, light sensing, the orexin/adenosine sleep-wake switch, restless-legs iron biology, and how fast you clear the "go" chemicals that keep a mind racing at bedtime.

• Hard to fall asleep at a conventional hour despite feeling tired
• An evening "second wind" of alertness
• Waking unrefreshed regardless of hours slept
• Severe morning grogginess (sleep inertia)
• Naturally very early, or very late, sleep and wake times
• Sleep timing that drifts later each day
• Poor tolerance of shift work, jet lag, or time changes
• Frequent night awakenings; fragmented, light sleep
• "Tired but wired"- exhausted body, racing mind
• Excessive daytime sleepiness or sleep attacks
• Cataplexy, sleep paralysis, or hypnagogic hallucinations
• Restless, crawling leg sensations at night
• Periodic leg movements / kicking in sleep
• Caffeine sensitivity- anxiety or insomnia from modest doses
• Mood that tracks the seasons or the light cycle
• Daytime fatigue, brain fog, poor concentration
• Reduced stress tolerance when sleep is short
• Cravings and weight gain linked to poor sleep
• Blood sugar or blood pressure changes with poor sleep
• Pre-sleep rumination and worry that won't switch off
• An afternoon coffee that reliably ruins your night
• Low ferritin or iron alongside restless legs
• Family history of extreme "lark" or "owl" sleep timing
• Free-running sleep (most common in blind individuals)

Answer the symptom questions below as honestly as you can. Combined with your DNA file, your answers help map which pathways are most worth your attention, and which support strategies give you the highest leverage.